Our Impact
Transforming research and redefining what’s possible. Our efforts to change the trajectory of ALS research are unlocking critical insights and accelerating the path to effective treatments.
A radical vision for major impact
At Target ALS, we didn’t just join the fight—we changed the rules.
Years of slow progress and the unrelenting speed of ALS inspired us to develop a revolutionary new model for research, the Innovation Ecosystem. Our approach is rapidly advancing the pace of science, breaking down barriers to progress, and fostering collaboration to enable discovery.
Through the research we fund, enable, and conduct, we are fast-tracking breakthroughs and uniting academia, pharma and biotech, venture capital, government, other ALS nonprofits, and the ALS community. Together, we are making research the highest form of care, and it’s showing.
Powering progress
Our game-changing model transforms how ALS research happens—and the impact is clear.
750+ research grants funded
Backing the most impactful science—free from bias or boundaries—to accelerate progress in ALS research.
$80M+ invested in ALS research
Funding research at every level to accelerate the path to breakthroughs.
58% of funded projects have led to drug discovery programs
Driving progress with a collaborative approach.
12 clinical trials developed from funded projects
Contributing directly to the launch of clinical trials that aim to bring new treatments to those living with ALS.
1800+ partners using our resources
Accelerating progress by offering no-strings-attached resources with our Research Cores to scientists around the world.
14 active global research sites
Conducting research through the largest and most inclusive global ALS study ever.
Real-world impact
Unlocking discovery
The next big ALS breakthrough could come from anywhere. That’s why access must drive innovation. We offer the global research community unrestricted, no-strings-attached access to some of the most comprehensive ALS biosample and tool collections available—resources that would otherwise be out of reach for many labs.
“Without Target ALS’s access to these stem cell lines, the process of creating such models would be significantly more costly and time-consuming… these stem cell banks are sometimes not publicly available, so it’s been instrumental in advancing our research.”
Sharing data without barriers
We’re speeding up the path to discoveries by breaking down barriers like paywalls, red tape, and intellectual property restrictions. Our Data Engine is a first-of-its-kind platform giving researchers around the world free access to powerful ALS data—all in one place.
Built in partnership with DNAstack and Verily, this Research Core includes easy-to-use tools to search, explore, and analyze multi-omic data linked to real biosamples.
The next big ALS breakthrough could come from anywhere. That’s why access must drive innovation. We offer the global research community unrestricted, no-strings-attached access to some of the most comprehensive ALS biosample and tool collections available—resources that would otherwise be out of reach for many labs.
We’re speeding up the path to discoveries by breaking down barriers like paywalls, red tape, and intellectual property restrictions. Our Data Engine is a first-of-its-kind platform giving researchers around the world free access to powerful ALS data—all in one place.
Built in partnership with DNAstack and Verily, this Research Core includes easy-to-use tools to search, explore, and analyze multi-omic data linked to real biosamples.
“The way I’ve used the resource thus far has really helped me with hypothesis generation… It’s a really big deal, because that stuff just takes so much time. Target ALS runs a very tight ship, so I have trusted this resource implicitly.”
Empowering global research
The research we conduct is unlocking insights by expanding the diversity and global reach of ALS studies. Our ALS Global Research Initiative (AGRI), with its Global Natural History Study and Community-Based Pop-Up Clinics, is the largest and most inclusive ALS research study ever.
While other studies collect samples and data, the critical information participants provide isn’t made available immediately, like in our studies. In some cases, samples can sit on shelves for years—further delaying urgently needed discoveries.
We invite communities into our studies and immediately deliver samples to accelerate progress.
Sustain our progress
Every discovery we enable, every insight we unlock, and every breakthrough we make begins with you. Join us to help change the future for people living with ALS.
